Upd. May 2023: Latest worthy addition: Fushisha no Deshi (Disciple of the Lich). 

Upd.:  I encountered several novels that blew up my top ranks in 2022.

I have a specific taste for Isekai novels, and I'm able to tolerate many things and sometimes even issues with the plot, world building and flatness of characters. But what I can say about this list you're about to witness, is that I'm positively able to re-read each and every of this novels, given the time.

In some cases, like Wortenia Senki and Hachinan Tte, I read both WN and LN, but I don't think it's needed to bother adding both versions to this list.

P.S.: While the list isn't fully complete, I'm starting slowly to add my biased comments for you to see.

P.P.S.: My memory is good, but I can still miss your favourite novel, if you think I did (I'm mostly talking about Isekai stuff), feel free to leave comment under the List. Most definitely I'll reply and if I didn't miss it for a reason, I'll add it (at least into my reading list, hehe).